카테킨이 함유된 치약의 우치 초기 우식법랑질에 대한 효과
Combinatorial Cariostatic Potential of Herbal Extracts and Fluoride.
홍석진, 박기철, 신영규, 손재범, 정성숙,
소속 상세정보
홍석진 ( ) - 전남대학교 치과대학 예방치과학교실
박기철 ( ) - 인디아나대학교 치과대학
신영규 ( ) - 전남대학교 식품공학과
손재범 ( ) - 전남대학교 치과대학 예방치과학교실
정성숙 ( ) - 전남대학교 치의학연구소
KMID : 0355420010250020185
Abstract
The purpose of this study was to compare the several combinatorial cariostatic potentials of experimental dentifrices containing an herbal extract, catechin, in combination of sodium fluoride and/or triclosan in silica base. The chemical and microbial cyclic remineralization procedures were used to measure the effect of each dentifrices. Subsurface caries lesions were prepared by exposing extracted, flattened and polished bovine enamel cores to lactate-Carbopol system for 48 hours. The delta VHNs were determined and analyzed by one-way ANOVA and Newman-Keul procedures for the multiple Student´s t-test as described previously.
The results of each test dentifrices are summarized as followings;
Effects of the different dentifrices on surface hardness according to pH cycling methods (delta VHN±S.D.)
Test Dentifrice (Silica Base) Chemical model Microbial model
Negative Control (No Active Agent) 8.3± 3.9 7.0± 6.0
Paste A (0.4% catechin) 11.8± 3.9 11.4± 5.0
Paste B (NaF & tridosan) 18.9± 5.6 28.2± 8.4
Positive Control (NO) 22.9± 5.3 22.0± 5.6
Paste C (NaF, tridosan & 0.4% catechin) 26.2± 10.0 43.6± 10.6
Colgate Total* (NaF & tridosan) 34.4± 8.7 51.4± 9.2
These results showed that (1) the addition of herbal component, catechin numerically increased surface hardness in both test models, (2) the fluoride dentifrices significantly increased surface hardness (p <0.05) as compared to the negative control, and (3) the specimens tested in the microbial cyclic model showed a highly significant cariostatic benefit of Paste C and Colgate Totaldentifrices (p (0.001) as compared to the other test dentifrices.
All the presented findings support the conclusion that catechin is enough to cariostatic effect if adden in toothpaste.
키워드
불화나트륨;카테킨;트리클로산;미세경도
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